Professor BA Denian is an elected member of the Chinese Academy of Engineering and the Institute of Medicine of the U.S. National Academies. He has dedicated his academic career to tumor immunology research. In the 1980s, he discovered a natural thymocytotoxic autoantibody, and proposed a theory to illustrate the relationship between abnormal immune function and hypertension, and thus is recognized as a pioneer of cancer biology and theory in China.